150356-97-1Relevant academic research and scientific papers
Cyclization of N-Cyanovinyl-lactam Imines to Condensed 4-Aminopyridines or Substituted Aminopyrazole
Paetzel, Michael,Ushmajev, Alexej,Liebscher, Juergen,Granik, Vladimir,Grisik, Sofia,Polievktov, Mikhail
, p. 1067 - 1068 (2007/10/02)
N-Cyanovinyl-lactam imines 2 react with hydrazine giving aminopyrazole 4a while lactam imine 3 is split off.Treatment of 2 with strong bases gives intramolecular cyclization to condensed 4-aminopyridines 5.The progress of reaction was observed by polarogr
