150417-17-7

Basic information

• Product Name: (S)-3-AMINOMETHYL-2-BOC-3,4-DIHYDRO-1H-ISOQUINOLINE
• Synonyms: (S)-3-AMINOMETHYL-2-BOC-3,4-DIHYDRO-1H-ISOQUINOLINE;2(1H)-Isoquinolinecarboxylic acid, 3-(aminomethyl)-3,4-dihydro-, 1,1-dimethylethyl ester, (3S)-
• CAS NO: 150417-17-7
• Molecular Formula: C₁₅H₂₂N₂O₂
• Molecular Weight: 262.35
• Mol File: 150417-17-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-3-AMINOMETHYL-2-BOC-3,4-DIHYDRO-1H-ISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-AMINOMETHYL-2-BOC-3,4-DIHYDRO-1H-ISOQUINOLINE(150417-17-7)
• EPA Substance Registry System: (S)-3-AMINOMETHYL-2-BOC-3,4-DIHYDRO-1H-ISOQUINOLINE(150417-17-7)

Safety Data

• Hazardous Substances Data: 150417-17-7(Hazardous Substances Data)

Usage

General Description

(S)-3-Aminomethyl-2-BOC-3,4-dihydro-1H-isoquinoline is a chemical compound that belongs to the class of isoquinoline derivatives. It contains an amino group and a BOC (tert-butoxycarbonyl) protecting group, making it useful in organic synthesis, especially in the preparation of pharmaceuticals. Isoquinoline derivatives are known for their diverse biological activities, including antiviral, antibacterial, antifungal, and anticancer properties. This particular compound can be used as a building block in the production of various drug molecules and other organic compounds. Its unique structure and reactivity make it valuable in the field of medicinal chemistry and drug development.

Upstream product

• 183958-71-6 tert-butyl (3S)-3-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 115962-35-1 (3S)-2-tert-butoxycarbonyl-1,2,3,4-tetrahydroisoquinole-3-carboxylic acid 
• 357339-32-3 Boc-L-Tic-CH₂N₃ 

Downstream Products

• 1042689-72-4 t-butyl (3S)-3-[(benzoylamino)methyl]-3,4-dihydroisoquinoline-2(1H)-carboxylate 
• 568587-94-0 2-[({3-[(3-phenyl-ureido)-methyl]-3,4-dihydro-1H-isoquinoline-2-carbothioyl}-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

NOVEL DIPEPTIDYL PEPTIDASE-IV INHIBITORS

The present invention relates to novel compounds exhibiting excellent inhibitory activity versus Dipeptidyl Peptidase-IV (DPP-IV), methods of preparing the same and pharmaceutical compositions containing the same as an active agent.

DPP-IV inhibitors

The invention relates to compounds of formula (I) wherein Z, R1-8, n, A1, X1 and X2 have the meaning as cited in the description and the claims. Said compounds are useful as DPP-IV inhibitors. The invention also

New scaffolds in the development of Mu opioid-receptor ligands

A new class of μ selective receptor antagonists has been developed using a combinatorial approach based on previously reported Dmt-Tic dipeptide ligands. Modified tetrahydroisoquinoline (Tiq) residues were reacted with different electrophiles in order to