150433-22-0 Usage
General Description
5-(tert-butyl)-3-(trifluoromethyl)-1H-pyrazole is a chemical compound that belongs to the pyrazole class of compounds. It is characterized by the presence of a tert-butyl and trifluoromethyl group on the pyrazole ring. 5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals due to its versatile reactivity and biological activity. The tert-butyl group provides steric hindrance, while the trifluoromethyl group enhances the compound's lipophilicity and metabolic stability. Additionally, these chemical features make 5-(tert-butyl)-3-(trifluoromethyl)-1H-pyrazole a valuable building block for the development of new drugs and agrochemicals with improved pharmacokinetic properties.
Check Digit Verification of cas no
The CAS Registry Mumber 150433-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,4,3 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 150433-22:
(8*1)+(7*5)+(6*0)+(5*4)+(4*3)+(3*3)+(2*2)+(1*2)=90
90 % 10 = 0
So 150433-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H3BrF4O/c9-5-3-4(1-2-6(5)10)7(14)8(11,12)13/h1-3H
150433-22-0Relevant articles and documents
5-Hydroxy-2-pyrazolines and some of their 1-substituted analogs
Zelenin,Tugusheva,Yakimovich,Alekseev,Zerova
, p. 668 - 676 (2007/10/03)
The use of 1,3-dicarbonyl compounds containing strong electron-withdrawing substituents (perfluoroalkyl, 4-nitrophenyl) at one of the carbonyl groups in reaction with hydrazine or its monosubstituted derivatives (4-nitro- and 2,4-dinitrophenylhydrazines) leads to the formation of stable intermediates for the synthesis of pyrazoles (5-hydroxy-2-pyrazolines) or their linear tautomers (hydrazones).
5-Hydroxy-4,5-Dihydropyrazoles
Zelenin, Kirill N.,Alekseyev, Valery V.,Tygysheva, Alja R.,Yakimovitch, Stanislav I.
, p. 11251 - 11256 (2007/10/02)
The use of β-diketones with strong electron-withdrawing substituents in reaction with hydrazine and its monosubstituted derivatives leads to the stable intermediates of pyrazole synthesis - 5-hydroxy-4,5-dihydropyrazoles or their open chain isomers.
