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150433-22-0

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150433-22-0 Usage

Description

5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is a pyrazole-based chemical compound distinguished by the presence of a tert-butyl and trifluoromethyl group on its pyrazole ring. 5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is known for its versatile reactivity and biological activity, with the tert-butyl group offering steric hindrance and the trifluoromethyl group contributing to enhanced lipophilicity and metabolic stability. These characteristics render 5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE a valuable building block in the development of new drugs and agrochemicals with improved pharmacokinetic properties.

Uses

Used in Pharmaceutical Industry:
5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is used as a synthetic intermediate for the development of pharmaceuticals. Its unique structural features allow for the creation of new drugs with enhanced pharmacokinetic properties, potentially leading to improved efficacy and reduced side effects.
Used in Agrochemical Industry:
In the agrochemical sector, 5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE serves as a key intermediate in the synthesis of agrochemicals. Its reactivity and biological activity contribute to the development of more effective and stable agrochemicals for crop protection and other agricultural applications.
Used as a Building Block in Medicinal Chemistry:
5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is utilized as a building block in medicinal chemistry for the design and synthesis of novel therapeutic agents. Its structural attributes facilitate the exploration of new chemical space and the optimization of drug candidates with desired pharmacological profiles.
Used in the Synthesis of Bioactive Molecules:
This pyrazole compound is employed in the synthesis of bioactive molecules with potential applications in various therapeutic areas. Its unique combination of steric and electronic properties enables the development of molecules with targeted biological activities and improved drug-like properties.
Used in the Development of Prodrugs:
5-(TERT-BUTYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE is also used in the design of prodrugs, which are biologically inactive compounds that are metabolized in the body to produce an active drug. Its presence in prodrug molecules can enhance their pharmacokinetic properties, leading to improved drug delivery and therapeutic efficacy.

Check Digit Verification of cas no

The CAS Registry Mumber 150433-22-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,4,3 and 3 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 150433-22:
(8*1)+(7*5)+(6*0)+(5*4)+(4*3)+(3*3)+(2*2)+(1*2)=90
90 % 10 = 0
So 150433-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H3BrF4O/c9-5-3-4(1-2-6(5)10)7(14)8(11,12)13/h1-3H

150433-22-0Downstream Products

150433-22-0Relevant articles and documents

5-Hydroxy-2-pyrazolines and some of their 1-substituted analogs

Zelenin,Tugusheva,Yakimovich,Alekseev,Zerova

, p. 668 - 676 (2007/10/03)

The use of 1,3-dicarbonyl compounds containing strong electron-withdrawing substituents (perfluoroalkyl, 4-nitrophenyl) at one of the carbonyl groups in reaction with hydrazine or its monosubstituted derivatives (4-nitro- and 2,4-dinitrophenylhydrazines) leads to the formation of stable intermediates for the synthesis of pyrazoles (5-hydroxy-2-pyrazolines) or their linear tautomers (hydrazones).

5-Hydroxy-4,5-Dihydropyrazoles

Zelenin, Kirill N.,Alekseyev, Valery V.,Tygysheva, Alja R.,Yakimovitch, Stanislav I.

, p. 11251 - 11256 (2007/10/02)

The use of β-diketones with strong electron-withdrawing substituents in reaction with hydrazine and its monosubstituted derivatives leads to the stable intermediates of pyrazole synthesis - 5-hydroxy-4,5-dihydropyrazoles or their open chain isomers.

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