15046-63-6Relevant academic research and scientific papers
Highly selective mono-substitution in Pd-catalyzed cross-coupling reactions of 3,6-dichloropyridazine with organozinc compounds
Chekmarev, Dmitriy S.,Stepanov, Alexander E.,Kasatkin, Alexander N.
, p. 1303 - 1305 (2007/10/03)
Pd-catalyzed cross-coupling reactions of 3,6-dichloropyridazine (1) with benzyl, aryl, and alkyl organozinc compounds led to selective mono-substitution of one of the chlorine atoms. The subsequent cross-coupling of the resulting monochlorides with RZnCl afforded unsymmetrical 3,6-carbon-disubstituted pyridazines.
