150479-67-7

Basic information

• Product Name: 2-aMinoisophthalaMide
• Synonyms: 2-aMinoisophthalaMide
• CAS NO: 150479-67-7
• Molecular Formula: C₈H₉N₃O₂
• Molecular Weight: 179.17596
• Mol File: 150479-67-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-aMinoisophthalaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-aMinoisophthalaMide(150479-67-7)
• EPA Substance Registry System: 2-aMinoisophthalaMide(150479-67-7)

Safety Data

• Hazardous Substances Data: 150479-67-7(Hazardous Substances Data)

Usage

Chemical compound

2-Aminoisophthalamide

Classification

Aminobenzenes

Physical state

Pale yellow solid

Molecular weight

151.16 g/mol

Uses

Building block for pharmaceuticals, dyes, and agrochemicals
Precursor for synthesis of various heterocyclic compounds
Key intermediate in production of organic products

Biological activities

Potential inhibitor of certain enzymes
Utilized in medicinal chemistry research

Upstream product

• 81-20-9 2,6-dimethylnitrobenzene 
• 21161-11-5 2-nitroisophthalic acid 
• 32114-73-1 2-nitrobenzene-1,3-dicarboxamide 

Downstream Products

• 1612242-53-1 C₂₅H₂₇F₃N₆O₃ 
• 1612241-66-3 4-(3-trifluoromethyl-benzylamino)-benzo[d][1,2,3]triazine-8-carboxamide 
• 1612241-86-7 4-((4-(3-(trifluoromethyl)phenyl)piperidin-3-yl)amino)benzo[d][1,2,3]triazine-8-carboxamide 

Relevant articles and documents

AZAQUINAZOLINE CARBOXAMIDE DERIVATIVES

Novel azaquinazoline carboxamide derivatives of formula (I) wherein W1, W2, W3, W4, R1, R2, R3 and m which are defined above, are p70S6K inhibitor, and can be employed, inter alia, for the treatment of hyperproliferative disorders.

QUINAZOLINONE ANTIANGINAL AGENTS

Compounds of formula: and pharmaceutically acceptable salts thereofwhereinR1 is H, Q - Q alkyl, C j -Q alkoxy or CONRsRs;R2 is H or- CJ-C4 alkyl;R3 is C2-C4 alkyl;R4 is H, C2-C4 alkanoyl optionally substituted withNR7R8, (hydroxy)C2-C4 alkyl optionally substitutedwith NR7R8, CH=CHC02R9, CH=CHCONR7R8,CH2CH2C02R9, CH2CH2CONR7R8, S02NR7R8,S02NH(CH2)nNR7R8 or imidazolyl;R5 and Rs are each independently H or C1-C4 alkyl;R7 and R8 are each independently H or C1-C4 alkyl, ortogether with the nitrogen atom to which they areattached form a pyrrolidino, piperidino, morpholino or4-(NR10)-l-piperazinyl group wherein any of saidgroups is optionally substituted with CONR5R6;R9 is H or C1-C4 alkyl;R10 is H, C1-C3 alkyl or (hydroxy)C2-C3 alkyl; andn is 2, 3 or 4;with the proviso that R4 is not H when R1 is H, C1-C4 alkylor C1-C4 alkoxy; are selective cGMP PDE inhibitors usefiilin the treatment of cardiovascular disorders such as angina, hypertension, heart failure and atherosclerosis.