150482-72-7

Basic information

• Product Name: (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL
• Synonyms: (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL;3(R)-AMINO-2-BENZYLAMINO-PROPAN-1-OL
• CAS NO: 150482-72-7
• Molecular Formula: C₁₀H₁₆N₂O
• Molecular Weight: 180.25
• Mol File: 150482-72-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL(150482-72-7)
• EPA Substance Registry System: (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL(150482-72-7)

Safety Data

• Hazardous Substances Data: 150482-72-7(Hazardous Substances Data)

Usage

General Description

(R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL is a chemical compound that belongs to the class of alcohols and amines. It is a chiral molecule, meaning it has a non-superposable mirror image. (R)-3-AMINO-2(BENZYLAMINO)PROPAN-1-OL has a primary amine group, a secondary amine group, and a hydroxyl group attached to a propan-1-ol backbone. It is commonly used as a building block in organic synthesis and pharmaceutical research due to its potential for forming various functionalized compounds. Additionally, it has been studied for its potential biological activities and therapeutic applications, particularly in the development of new drugs.

Upstream product

• 142811-44-7 N-benzyl-L-serinamide hydrochloride 
• 17136-44-6 N-benzyl-L-serine methyl ester hydrochloride 
• 142811-44-7 N-benzyl-D-serinamide hydrochloride 
• 17136-44-6 N-benzyl-D-serine methyl ester hydrochloride 

Downstream Products

• 142811-49-2 N-<4-<<2(R)--3-<(2-amino-5-nitro-4(3H)-oxopyrimidin-6-yl)amino>propyl>amino>benzoyl>-L-glutamic acid 
• 142811-49-2 N-<4-<<2(S)--3-<(2-amino-5-nitro-4(3H)-oxopyrimidin-6-yl)amino>propyl>amino>benzoyl>-L-glutamic acid 
• 142811-46-9 2-amino-6<<2'(S)-(benzylamino)-3'-hydroxypropyl>amino>-5-nitro-4(3H)-pyrimidinone 
• 142811-46-9 2-amino-6<<2'(R)-(benzylamino)-3'-hydroxypropyl>amino>-5-nitro-4(3H)-pyrimidinone 

Relevant articles and documents

Synthesis of Tetrahydropteridine C6-Stereoisomers, Including N5-Formyl-(6S)-tetrahydrofolic Acid

Chiral N1-protected vicinal diamines derived from amino acids were condensed with 2-amino-6-chloro-5-nitro-4(3H)-pyrimidinone, the nitro group reduced, and the amine deprotected.Oxidative cyclization of the resulting triaminopyrimidinone via quinoid pyrimidine intermediates gave a quinoid dihydropteridine, which was then reduced to a tetrahydropteridine C6-stereoisomer.Thus, 6(R)- and 6(S)-propyltetrahydropterin were stereospecifically synthesized (99 percent enantiomeric purity) in good yield from D- and L-norvaline, respectively.Reductive alkylation of (p-aminobenzoyl)-L-glutamate with a niropyrimidine aldehyde derived from D- or L-serine similarly afforded, after cyclization and reduction, (6R)- or (6S)-tetrahydrofolic acid.The latter was then converted to the natural isomer of leucovorin by regioselective N5-formylation with carbonyl diimidazole / formic acid without loss of enantiomeric purity.