150536-23-5Relevant articles and documents
The Preparation of Perfluoroaryl Substituted Isoxazoles via Nucleophilic Aromatic Substitution with Lithioalkylisoxazoles
Xia, Xiongbing,Knerr, Gary,Natale, N. R.
, p. 1297 - 1299 (2007/10/02)
The lithioalkylisoxazoles obtained from C-5 lateral metalation of alkylisoxazoles, 1, add to hexafluorobenzene.When the C-4 substituent was an electron withdrawing tertiary amide moiety, the yields were highest for mono-perfluoroarylation to give 5-pentafluorophenylmethylisoxazoles, 2.