15057-24-6

Basic information

• Product Name: 1-(furan-2-yl)-5-phenylpenta-2,4-diyn-1-one
• CAS NO: 15057-24-6
• Molecular Formula: C₁₅H₈O₂
• Molecular Weight: 220.2228
• Mol File: 15057-24-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 355.4°C at 760 mmHg
• Flash Point: 167.4°C
• Density: 1.23g/cm³
• Vapor Pressure: 3.13E-05mmHg at 25°C
• Refractive Index: 1.627
• CAS DataBase Reference: 1-(furan-2-yl)-5-phenylpenta-2,4-diyn-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(furan-2-yl)-5-phenylpenta-2,4-diyn-1-one(15057-24-6)
• EPA Substance Registry System: 1-(furan-2-yl)-5-phenylpenta-2,4-diyn-1-one(15057-24-6)

Safety Data

• Hazardous Substances Data: 15057-24-6(Hazardous Substances Data)

Upstream product

• 932-87-6 1-Bromo-2-phenylacetylene 
• 1257555-37-5 1-(furan-2-yl)-5-phenylpenta-2,4-diyn-1-ol 
• 695-82-9 furyl ethynyl carbinol 

Relevant articles and documents

Gold-Catalyzed Oxidative Cyclization Involving Nucleophilic Attack to the Keto Group of α,α′-Dioxo Gold Carbene and 1,2-Alkynyl Migration: Synthesis of Furan-3-carboxylates

A multicomponent strategy for the synthesis of functionalized furan-3-carboxylates based on gold-catalyzed oxidative cyclization of diynones with alcohols or water has been developed. Mechanistic studies revealed that a rare nucleophilic attack to the carbonyl group of the α,α′-dioxo gold carbene instead of the carbene center and 1,2-alkynyl group migration were involved in this transformation. This method offers several advantages such as mild conditions, high regio- and chemoselectivity, and wide functional group compatibility.