150586-19-9

Upstream product

• 56-06-4 2,6-diaminopyrimidin-4-ol 
• 389625-30-3 4-(2-bromo-3-oxo-propyl)-benzoic acid tert-butyl ester 
• 134372-99-9 3-(4-<2,2-dimethylethyl>carboxyphenyl)-1-propanal 

Downstream Products

• 150585-92-5 diethyl N-{4-[(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)methyl]benzoyl}-L-glutamate 

Relevant academic research and scientific papers

Pyrrolo[2,3-d]pyrimidine thymidylate synthase inhibitors: Design and synthesis of one-carbon bridge derivatives

A series of novel pyrrolo[2,3-d]pyrimidine derivatives was designed and synthesized as thymidylate synthase (TS) inhibitors. Molecular design was performed on the human TS complex model built on the basis of the reported structure of TS-deoxyuridinemonoph