15059-14-0Relevant academic research and scientific papers
Saccharin-based μ-oxo imidoiodane: A readily available and highly reactive reagent for electrophilic amination
Yoshimura, Akira,Koski, Steven R.,Fuchs, Jonathan M.,Saito, Akio,Nemykin, Victor N.,Zhdankin, Viktor V.
, p. 5328 - 5331 (2015)
Three new saccharin-based hypervalent iodine compounds were prepared by the reaction of saccharine with (diacetoxyiodo)arenes or acetoxybenziodoxole. Structures of these new imidoiodanes were established by X-ray crystallography. The saccharin-based μ-oxo-bridged imidoiodane readily reacts with silyl enol ethers under mild conditions to give the corresponding α-aminated carbonyl compounds in moderate yields. Sweet saccharin: Three new saccharin-derived hypervalent iodine compounds were prepared by the reaction of saccharine with (diacetoxyiodo)arenes or acetoxybenziodoxole. The saccharin-based μ-oxo-bridged imidoiodane readily reacts with silyl enol ethers to give the corresponding α-aminated carbonyl compounds in moderate yields.
