150620-22-7

Upstream product

• 150620-20-5 C₃₂H₄₈N₄O₁₁SSi 
• 150620-19-2 Acetic acid (2R,3R,4R,5S)-5-acetoxymethyl-4-(2-methanesulfonyloxy-ethyl)-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 150620-18-1 Acetic acid (2R,3R,4R,5S)-5-acetoxymethyl-4-(2-hydroxy-ethyl)-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 144944-85-4 2',5'-di-O-acetyl-3'-deoxy-3'-C-(2-hydroxyethyl)-2-O-para-methoxyphenyl-(β-D-ribofuranosyl)thymine 
• 144944-96-7 3’-O-tert-butyldimethylsilyl-5’-deoxy-5’-mercaptothymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 108-24-7 acetic anhydride 

Downstream Products

• 150620-23-8 C₄₅H₅₀N₄O₁₂S 

Relevant academic research and scientific papers

Synthesis of 2'-substituted sulfide-linked dinucleotides

3'-Deoxy-3'-(2-mesyloxyethyl)ribofuranosylthymine derivative 3, and its 2'-methoxy (16) and 2'-deoxy (38) analogs were condensed with 5'-deoxy-5'- thiothymidine 4 and 17 or 2'-O-methyl-5'-deoxy-5'-thiouridine 34 and 37 to provide, after standard functional group transformations, thymidine-thymidine and uridine-thymidine dimers 9, 21, 43 and 47. Oxidation of model sulfide dimer 48 with oxone gave sulfone 49. It was not stable to 27% ammonia.