150637-99-3

Upstream product

• 936226-23-2 2-bromo-3-methoxy-cyclohex-2-enone oxime 
• 108-24-7 acetic anhydride 
• 150637-98-2 2,4,6-Tribromo-3-methoxydiacetanilide 
• 36255-23-9 2,4,6-tribromo-3-methoxyaniline 
• 536-90-3 m-Anisidine 

Downstream Products

• 1314091-75-2 C₁₃H₁₂N₂O₅S 
• 67853-38-7 2-bromo-3-methoxyphenylamine hydrochloride 

Relevant academic research and scientific papers

PROCESS FOR PREPARING SUBSTITUTED ANISIDINES

Disclosed is a process for preparing substituted anisidines of formula I starting from substituted cyclic hydroxy-ketones II via aromatization through a substituted oxime intermediate IV in which R is C1-C6 alkyl or halogen, and Alk is C1-C6 alkyl. The su

Synthesis of 2,6-disubstituted and 2,3,6-trisubstituted anilines

A number of 2,6-disubstituted and 2,3,6-trisubstituted anilines have been prepared via the selective para dehalogenation of the corresponding anilines. Modification of the substituents on the amino nitrogen demonstrates that the selectivity is derived from steric rather than electronic effects. The effects of the choice of formate hydrogen donor, Pd catalyst, solvent, and temperature upon the efficiency and selectivity of the dehalogenation are discussed.