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p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 150726-07-1 Structure
  • Basic information

    1. Product Name: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide
    2. Synonyms:
    3. CAS NO:150726-07-1
    4. Molecular Formula:
    5. Molecular Weight: 487.577
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 150726-07-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(150726-07-1)
    11. EPA Substance Registry System: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(150726-07-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 150726-07-1(Hazardous Substances Data)

150726-07-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 150726-07-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,7,2 and 6 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 150726-07:
(8*1)+(7*5)+(6*0)+(5*7)+(4*2)+(3*6)+(2*0)+(1*7)=111
111 % 10 = 1
So 150726-07-1 is a valid CAS Registry Number.

150726-07-1Relevant articles and documents

Modifications and structure-activity relationships at the 2-position of 4-sulfonamidopyrimidine derivatives as potent endothelin antagonists

Morimoto, Hiroshi,Shimadzu, Hideshi,Hosaka, Toshihiro,Kawase, Yasushi,Yasuda, Kosuke,Kikkawa, Kohei,Yamauchi-Kohno, Rikako,Yamada, Koichiro

, p. 81 - 84 (2007/10/03)

To improve water solubility and to study structure-activity relationships, we modified the structure of the pyrimidine nucleus of each of a series of potent ETA antagonists, 3a and 4a, at the 2-position. In a previous study, each of these antag

Discovery of Ro 48-5695: A potent mixed endothelin receptor antagonist optimized from Bosentan

Neidhart, Werner,Breu, Volker,Burri, Kaspar,Clozel, Martine,Hirth, Georges,Klinkhammer, Uwe,Giller, Thomas,Ramuz, Henri

, p. 2223 - 2228 (2007/10/03)

Implementation of a pyridylcarbamoyl group and an isopropylpyridylsulfonamide substituent as key components in the scaffold of Bosentan resulted in the identification of the potent orally active endothelin receptor antagonist Ro 48-5695. It shows affinities for ET(A) and ET(B) receptors in the low nanomolar range and high functional antagonistic potency in vitro.

SULFONAMIDES

-

, (2008/06/13)

The novel sulfonamides of formula I, STR1 in which the symbols R. sup.1-R 9, R a, R b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms and angina pectoris.

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