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1507388-49-9

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1507388-49-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1507388-49-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,0,7,3,8 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1507388-49:
(9*1)+(8*5)+(7*0)+(6*7)+(5*3)+(4*8)+(3*8)+(2*4)+(1*9)=179
179 % 10 = 9
So 1507388-49-9 is a valid CAS Registry Number.

1507388-49-9Downstream Products

1507388-49-9Relevant articles and documents

Synthesis of novel 5-arylidenethiazolidinones with apoptotic properties: Via a three component reaction using piperidine as a bifunctional reagent

Bathula, Chandramohan,Tripathi, Sayantan,Srinivasan, Ramprasad,Jha, Kunal Kumar,Ganguli, Arnab,Chakrabarti,Singh, Shailja,Munshi, Parthapratim,Sen, Subhabrata

supporting information, p. 8053 - 8063 (2016/09/09)

The synthesis of a new library of 5-arylidenethiazolidinone compounds using an efficient three component reaction with thiazolidine-2,4-dione, piperidine and appropriate aldehydes is reported. This reaction is excellently high yielding, tolerant towards a variety of aldehydes and provides access to these compounds in a single step (in comparison to low yielding multistep syntheses reported in the literature). Once the reaction is complete, the desired product precipitates out of the reaction mixture and is isolated by filtration and purified by washing and recrystallization. These compounds revealed anti-proliferative activities against human breast cancer cells (MCF7 and MDA). Phenotypic profiling established the most active compound 17i (EC50 = 4.52 μM) as an apoptotic agent. A novel chemical proteomics approach identified β-actin-like protein 2, γ-enolase and macrophage migration inhibitory factor (MMIF) as putative cellular binding partners of 17i.

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