150766-36-2Relevant academic research and scientific papers
Arylcycloalkyl derivatives, their production and their use
-
, (2008/06/13)
Compounds of formula I, and the physiologically tolerable salts thereof, wherein the substituents R1-R4 have the meanings given in the specifications and show an activity against inflammatory conditions.
Structure-activity relationship studies of flavopiridol analogues
Murthi, Krishna K.,Dubay, Marja,McClure, Christopher,Brizuela, Leonardo,Boisclair, Michael D.,Worland, Peter J.,Mansuri, Muzammil M.,Pal, Kollol
, p. 1037 - 1041 (2007/10/03)
Cyclin dependent kinases (CDKs) along with the complementary cyclins form key regulatory checkpoint controls on the cell cycle. Flavopiridol is a synthetic flavone that shows potent and selective cyclin-dependent kinase inhibitory activity. In this paper, we report modifications of the 3-hydroxy-1-methylpiperidinyl (D ring) of flavopiridol and their effect on CDK inhibitory activity. (C) 2000 Elsevier Science. All rights reserved.
Arylcycloalkyl derivatives, their production and their use
-
, (2008/06/13)
Compounds of formula I, STR1 wherein the substituents R1 -R4 and a have the given meanings and show an activity against inflammatory conditions.
