1508260-88-5

Basic information

• Product Name: (Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcyclohexanol]ester, 99%
• Synonyms: (Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcyclohexanol]ester, 99%
• CAS NO: 1508260-88-5
• Molecular Formula: C17H27O3P
• Molecular Weight: 310.368241
• Product Categories: Chiral Phosphine
• Mol File: 1508260-88-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 412.2±47.0 °C(Predicted)
• Appearance: white/Powder
• Density: 1.09±0.1 g/cm3(Predicted)
• PKA: 12.78±0.10(Predicted)
• Stability: hygroscopic
• CAS DataBase Reference: (Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcyclohexanol]ester, 99%(CAS DataBase Reference)
• NIST Chemistry Reference: (Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcyclohexanol]ester, 99%(1508260-88-5)
• EPA Substance Registry System: (Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcyclohexanol]ester, 99%(1508260-88-5)

Safety Data

• Hazardous Substances Data: 1508260-88-5(Hazardous Substances Data)

Usage

General Description

The chemical "(Sp)-HydroxyMethylphenylphosphinic acid [(-)-(1R,2S,2R)-2-i-propyl-5-Methylcjsonancyclohexanol] ester, 99%" is a compound that is commonly used in chemical and pharmaceutical research. It is an ester derivative of hydroxymethylphenylphosphinic acid, which is known for its potential as an organic phosphate scavenger. The compound is obtained in high purity, with a 99% content, making it suitable for use in various laboratory applications. It is also a chiral compound, with a specific stereochemistry denoted by the (Sp) prefix, indicating its potential for asymmetric synthesis and other stereochemically controlled reactions. Overall, the compound is a valuable tool for researchers working in the fields of organic synthesis and medicinal chemistry.

Upstream product

• 50-00-0 formaldehyd 
• 31352-60-0 (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexyl phenylphosphinate 
• 31352-60-0 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl phenylphosphinate 
• 1508260-96-5 menthyl (acetylmethyl)-H-phosphinate 
• 2216-51-5 (-)-menthol 
• 108-86-1 bromobenzene 
• 1779-48-2 phenylphosphinic acid 

Relevant articles and documents

Preparation of enantiomerically pure α-hydroxyl phosphinates via hydrophosphorylation of aldehydes with H-phosphinate

The hydrophosphorylation of aldehydes with a P-stereogenic H-phosphinate was realized by heating two compounds in a neat state or catalyzed by a base, to afford P-retention α-hydroxyl phosphinates. The (SP,SC) and other diastereomers were isolated, and their structures were confirmed by NMR spectroscopy and crystallography.

Manganese-Mediated Intermolecular Arylation of H-Phosphinates and Related Compounds

The intermolecular radical functionalization of arenes with aryl and alkyl H-phosphinate esters, as well as diphenylphosphine oxide and H-phosphonate diesters, is described. The novel catalytic MnII/excess MnIVsystem is a convenient

A general strategy for the synthesis of P-stereogenic compounds

A great leap forward toward the general synthesis of P-stereogenic compounds: Heating H3PO2 with (-)-menthol and paraformaldehyde gives easily crystallized menthyl hydroxymethyl-H-phosphinate (1). From this product, virtually any P-s