150863-84-6 Usage
Chemical compound
6-chloro-9-(2-deoxy-2-fluororibofuranosyl)purine
Derivative of purine nucleoside
Composed of 6-chloropurine base and 2-deoxy-2-fluororibofuranosyl ribose sugar
Studied for cancer treatment
Potential use in leukemia and lymphoma treatment due to inhibitory effects on DNA and RNA synthesis
Antiviral properties
Research on effectiveness against hepatitis C virus
Nucleoside analog
Chemical structure allows interference with replication of viral and cancerous cells
Pharmaceutical development
Promising candidate for further research and development in the pharmaceutical industry
Check Digit Verification of cas no
The CAS Registry Mumber 150863-84-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,8,6 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 150863-84:
(8*1)+(7*5)+(6*0)+(5*8)+(4*6)+(3*3)+(2*8)+(1*4)=136
136 % 10 = 6
So 150863-84-6 is a valid CAS Registry Number.
InChI:InChI=1/C10H10ClFN4O3/c11-8-6-9(14-2-13-8)16(3-15-6)10-5(12)7(18)4(1-17)19-10/h2-5,7,10,17-18H,1H2/t4-,5-,7-,10-/m1/s1
150863-84-6Relevant articles and documents
Synthesis and anti-HIV activity of 6-substituted purine 2'-deoxy-2'- fluororibosides
Maruyama,Utzumi,Sato,Richman
, p. 527 - 537 (2007/10/02)
3',5'-Di-O-protected 6-chloropurine arabinoside 4b was treated with diethylaminosulfur trifluoride (DAST) and subsequently deprotected with pyridinium p-toluenesulfonate to give 6-chloropurine 2'-deoxy-2'- fluororiboside 6a. The displacement with nucleophile afforded the 6- substituted congener 6b-e. Treatment of 5'-O-protected 6-chloropurine arabinoside 3c with DAST gave lyxoepoxide 7.
