150864-95-2

Basic information

• Product Name: 1-Ethyl-cyclopropanecarboxylic acid
• Synonyms: 1-Ethyl-cyclopropanecarboxylic acid;1‐ethylcyclopropane‐1‐carboxylic acid
• CAS NO: 150864-95-2
• Molecular Formula: C6H10O2
• Molecular Weight: 114.15
• Mol File: 150864-95-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 198.9±8.0 °C(Predicted)
• Appearance: /
• Density: 1.124±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 4.86±0.20(Predicted)
• CAS DataBase Reference: 1-Ethyl-cyclopropanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Ethyl-cyclopropanecarboxylic acid(150864-95-2)
• EPA Substance Registry System: 1-Ethyl-cyclopropanecarboxylic acid(150864-95-2)

Safety Data

• Hazardous Substances Data: 150864-95-2(Hazardous Substances Data)

Usage

General Description

1-Ethyl-cyclopropanecarboxylic acid is a chemical compound with the molecular formula C7H12O2. It is a carboxylic acid that contains a cyclopropane ring and an ethyl group. 1-Ethyl-cyclopropanecarboxylic acid is commonly used as a building block in organic synthesis and pharmaceutical research. It has been studied for its potential applications in medicinal chemistry, including as a precursor in the synthesis of bioactive compounds. Additionally, 1-Ethyl-cyclopropanecarboxylic acid may have potential uses in the development of new materials and as a chemical intermediate in various industrial processes. Overall, this chemical shows promise for a variety of applications in the fields of chemistry and materials science.

Upstream product

• 130287-75-1 2-tert-pentyl-4,4-dimethyl-4,5-dihydrooxazole 
• 1194258-22-4 1,1-dimethylethyl 1-ethylcyclopropanecarboxylate 
• 1447944-39-9 benzyl 1-vinylcyclopropanecarboxylate 
• 664364-37-8 benzyl 1-acetylcyclopropanecarboxylate 
• 5856-77-9 2,2-dimethylbutanoyl chloride 
• 595-37-9 2,2-dimethylbutyric acid 
• 918522-58-4 2-(1-iodo-2-(iodomethyl)butan-2-yl)-4,4-dimethyl-4,5-dihydrooxazole 
• 918522-82-4 2-(1-ethylcyclopropyl)-4,4-dimethyl-4,5-dihydrooxazole 

Downstream Products

• 1448600-50-7 C₁₂H₁₆BrN 
• 1448600-32-5 C₁₂H₁₄BrNO 
• 1448599-98-1 N-(2-bromophenyl)-N-((1-ethylcyclopropyl)methyl)-1,1,1-trifluoromethanesulfonamide 

Relevant articles and documents

Converting gem-dimethyl groups into cyclopropanes via Pd-catalyzed sequential C-H activation and radical cyclization

(Diagram presented) A novel route to the synthesis of cyclopropane derivatives is described. 1,1-Dimethyls in 2-(1,1-dimethylalkyl) dimethyloxazolines are first converted into 1,3-diiodide derivatives via Pd-catalyzed sequential C-H activation and then radically cyclized to provide 2-(1-alkylcylclopropyl)-dimethyloxazolines. The use of EtOAc as a solvent is crucial for the diiodination of the functionalized substrates.

Pd(II)-Catalyzed Enantioselective C(sp3)-H Arylation of Free Carboxylic Acids

A monoprotected aminoethyl amine chiral ligand based on an ethylenediamine backbone was developed to achieve Pd-catalyzed enantioselective C(sp3)-H arylation of cyclopropanecarboxylic and 2-aminoisobutyric acids without using exogenous directing groups. This new chiral catalyst affords new disconnection for preparing diverse chiral carboxylic acids from simple starting materials that are complementary to the various ring forming approaches.

Organic compounds

The present invention concerns prostaglandins having a cyclopropane ring in the 2,3 position.