150878-36-7 Usage
General Description
6-Chloro-4-cyclopropyl-1H-quinazolin-2-one is a chemical compound with the molecular formula C11H8ClN3O. It belongs to the class of quinazolinone derivatives and is characterized by its cyclopropyl and chloro functional groups. 6-Chloro-4-cyclopropyl-1H-quinazolin-2-one has been studied for its potential pharmaceutical applications, particularly in the development of new drugs for various medical conditions. It has been found to exhibit interesting biological activities, making it a subject of interest for medicinal chemistry research. Additionally, its unique structure and properties make it a valuable target for synthetic strategies and chemical transformations. Overall, 6-Chloro-4-cyclopropyl-1H-quinazolin-2-one holds promise as a versatile and valuable chemical compound with potential utility in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 150878-36-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,8,7 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 150878-36:
(8*1)+(7*5)+(6*0)+(5*8)+(4*7)+(3*8)+(2*3)+(1*6)=147
147 % 10 = 7
So 150878-36-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H9ClN2O/c12-7-3-4-9-8(5-7)10(6-1-2-6)14-11(15)13-9/h3-6H,1-2H2,(H,13,14,15)
150878-36-7Relevant articles and documents
Chiral resolution process
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, (2008/06/13)
A chiral resolution process is described for the purification of a substituted chiral quinazoline, by salt formation with a resolving agent, followed by crystallization.
Synthesis of a series of 4-(arylethynyl)-6-chloro-4-cyclopropyl-3,4- dihydroquinazolin-2(1H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors
Tucker,Lyle,Wiscount,Britcher,Young,Sanders,Lumma,Goldman,O'Brien,Ball,Homnick,Schleif,Emini,Huff,Anderson
, p. 2437 - 2444 (2007/10/02)
As part of an ongoing effort to prepare novel non-nucleoside inhibitors of human immunodeficiency virus type-1 (HIV-1) reverse transcriptase (RT), a series of 4-(arylethynyl)-6-chloro-4-cyclopropyl-3,4-dihydroquinazolin- 2(1H)-ones 4aa-1 has been prepared