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150885-25-9

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150885-25-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 150885-25-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,0,8,8 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 150885-25:
(8*1)+(7*5)+(6*0)+(5*8)+(4*8)+(3*5)+(2*2)+(1*5)=139
139 % 10 = 9
So 150885-25-9 is a valid CAS Registry Number.
InChI:InChI=1/C11H14N4O5/c12-9-4-1-2-15(6(4)10(19)14-13-9)11-8(18)7(17)5(3-16)20-11/h1-2,5,7-8,11,16-18H,3H2,(H2,12,13)(H,14,19)/t5-,7-,8-,11-/m1/s1

150885-25-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-1-β-D-ribofuranosylpyrrole<2,3-d>pyridazin-7(6H)-one

1.2 Other means of identification

Product number -
Other names 4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1,6-dihydro-pyrrolo[2,3-d]pyridazin-7-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:150885-25-9 SDS

150885-25-9Downstream Products

150885-25-9Relevant articles and documents

Synthesis, Antiproliferative, and Antiviral Activity of 4-Amino-1-(β-D-ribofuranosyl)pyrrolopyridazin-7(6H)-one and Related Derivatives

Meade, Eric A.,Wotring, Linda L.,Drach, John C.,Townsend, Leroy B.

, p. 3834 - 3842 (2007/10/02)

The synthesis of 4-amino-1-β-D-ribofuranosylpyrrolopyridazin-7(6H)-one (3) from the reaction of ethyl 3-cyano-1-β-D-ribofuranosylpyrrole-2-carboxylate (10) and hydrazine is described.The 5:6 pyrrolopyridazin-7(6H)-one structure of 3 was established via a three-step conversion of 3 into 1-β-D-ribofuranosylpyrrolopyridazin-4,7(5H,6H)-dione (14). 4-amino-3-chloro-1-β-D-ribofuranosylpyrrolopyridazin-7(6H)-one (16) and 4-amino-3-bromo-1-β-D-ribofuranosylpyrrolopyridazin-7(6H)-one (18) were prepared via N-chlorosuccinimide or N-bromosuccinimide treatment of 4-amino-1-(2,3,5-tri-O-benzyl-β-D-ribofuranosyl)pyrrolopyridazin-7(6H)-one (7) followed by a removal of the benzyl groups with boron trichloride.Direct treatment of 3 with N-iodosuccinimide furnished 4-amino-3-iodo-1-β-D-ribofuranosylpyrrolopyridazin-7(6H)-one (19).The antiproliferative activity of the compounds was determined in L1210, H.Ep. 2 and several additional human tumor cell lines.In L1210 cells, the 3-halosubstituted compounds 16, 18, and 19 exhibited significant cytotoxicity (IC50 = 0.2, 0.1, 0.08 μM, respectively), in contrast to the 3-unsubstituted compound 3, which had only slight activity.The greater antiproliferative activity of 18 and 19 in contrast to 3 was confirmed in H.Ep. 2 cells and KB cells.The antiviral evaluation of these compounds revealed that compounds 16, 18, and 19 were active against human cytomegalovirus in both plaque- and yield-reduction assays.However, this activity was only partially separated from cytotoxicity in human cell lines.

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