150989-58-5

Upstream product

• 2228-79-7 1,5,6,7-Tetrahydro-2H-azepin-2-one 

Downstream Products

• 150989-60-9 3-Amino-1-(benzyloxycarbonyl)-4-hydroxyhexahydro-1H-azepine 
• 150989-61-0 4(R,S)-amino-3(R,S)-hydroxyazepane-1-carboxylic acid benzyl ester 
• 150989-59-6 8-oxo-3-azabicyclo[5.1.0]octane-3-carboxylic acid benzyl ester 
• 74472-27-8 1-(Benzyloxycarbonyl)hexahydro-1H-azepine 
• 150989-62-1 2,3,4,7-tetrahydro-azepine-1-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Synthesis of (3R,4R)-3-Amino-4-hydroxyhexahydroazepine, the Chiral Constituent of the Antibiotic Ophiocordin

(3R,4R)-3-Amino-4-hydroxyhexahydroazepine (2), the optically active constituent of the antifungal antibiotic ophicordin (1), was prepared in a multistep synthesis starting from D-serine.The absolute configuration was unambigously assigned by a comparison of the synthesized stereoisomer 2 with its racemate and the chiral moiety of the antibiotic ophiocordin by enantioselective gas chromatography. Key Words: 3-Amino-4-hydroxyhexahydroazepine / Cordyceps ophioglossoides / Antifungals / Antibiotics / Ophiocordin