1509921-68-9Relevant articles and documents
β-Sultams exhibit discrete binding preferences for diverse bacterial enzymes with nucleophilic residues
Kolb, Roman,Bach, Nina C.,Sieber, Stephan A.
supporting information, p. 427 - 429 (2014/01/06)
β-Sultams are potent electrophiles that modify nucleophilic residues in selected enzyme active sites. We here identify and characterize some of the specific bacterial targets and show a unique inhibition of the azoreductase family.