150993-49-0Relevant academic research and scientific papers
Diastereoselective synthesis of β-amino-α-hydroxy phosphonates via oxazaborolidine catalyzed reduction of β-phthalimido-α-keto phosphonates
Barco, Achille,Benetti, Simonetta,Bergamini, Paola,De Risi, Carmela,Marchetti, Paolo,Pollini, Gian P.,Zanirato, Vinicio
, p. 7705 - 7708 (2007/10/03)
Reduction of β-phthalimido-α-keto phosphonates, obtained through an Arbuzov reaction between the appropriate acid chloride and triethyl phosphite, with boranes and oxazaborolidine as catalyst, afforded β-phthalimido-α-hydroxy phosphonates in good yields and high diastereoselectivity. Deprotection of the amino group gave the title compounds.
Stereodivergent synthesis of β-amino-α-hydroxyphosphonic acid derivatives by Lewis acid mediated stereoselective hydrophosphonylation of α-amino aldehydes
Yokomatsu,Yamagishi,Shibuya
, p. 1401 - 1404 (2007/10/02)
The highly diastereoselective synthesis of β-amino-α-hydroxyphosphonic acid derivatives was achieved by Lewis acid mediated hydrophosphonylation of α-dibenzylamino aldehyde. Diastereofacial differentiation could be controlled in either a chelation or a no
