151052-96-9Relevant academic research and scientific papers
Extracyclic Stereocontrolled Alkylation of (1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one. A Highly Stereocontrolled Synthesis of (-)-Kanshone A
Kato, Michiharu,Watanabe, Masataka,Awen, Bahlul, Z.
, p. 5145 - 5152 (2007/10/02)
(1R,5S)-4-Ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one (7) was prepared from (+)-nopinone (1) in six steps and 70percent overall yield via (1R,5R)-6,6-dimethyl-3-(phenylthio)bicyclohept-3-en-2-one (2).Alkylation reactions of 7
REGIO- AND DIASTEREOSELECTIVE ALKYLATION OF (1R,5S)-4-ETHYL-6,6-DIMETHYL-3-(PHENYLSULFONYL)BICYCLOHEPT-3-EN-2-ONE
Kato, Michiharu,Watanabe, Masataka,Awen, Bahlul Z.,Vogler, Bernhart
, p. 7439 - 7442 (2007/10/02)
Alkylation of (1R,5S)-4-ethyl-6,6-dimethyl-3-(phenylsulfonyl)bicyclohept-3-en-2-one (3) with allyl bromide proceeded at the γ position to the conjugated enone system in regio- and diastereoselective fashion, providing (1R,5S)-4-((1R)-1-methyl-3-but
