151056-78-9 Usage
General Description
Methyl 6-chlorooxoindoline-3-carboxylate is a chemical compound consisting of a methyl group, a chlorine atom, and an oxoindoline-3-carboxylate moiety. METHYL 6-CHLOROOXOINDOLINE-3-CARBOXYLATE is a derivative of the indoline class of organic compounds, which are commonly used as pharmaceutical intermediates and building blocks for biologically active molecules. Methyl 6-chlorooxoindoline-3-carboxylate has potential applications in the fields of medicinal chemistry and drug discovery, as it may exhibit various biological activities due to its structural features. Additionally, this compound can be used in the synthesis of novel compounds with potential pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 151056-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,0,5 and 6 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 151056-78:
(8*1)+(7*5)+(6*1)+(5*0)+(4*5)+(3*6)+(2*7)+(1*8)=109
109 % 10 = 9
So 151056-78-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H8ClNO3/c1-15-10(14)8-6-3-2-5(11)4-7(6)12-9(8)13/h2-4,8H,1H3,(H,12,13)
151056-78-9Relevant articles and documents
AN IMPROVED PROCESS FOR PREPARING 2-OXINDOLES OF FORMULA I, A KEY RAW MATERIAL FOR MAKING PHARMACEUTICAL DRUGS AND INTERMEDIATES THEREOF
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Page/Page column 50, (2013/07/05)
The present invention provides an improved processes having practical utility for preparing 2-oxindoles of formula I comprising preparation of 2-nitroarylmalonate diester of formula II as first intermediate and subsequent insitu reductive cyclisation using metal acid combination and its modified work-up to form compound of formula I free from metal generated impurity of formula M(OH)X wherein M is metal cation and X is anion. R is selected from hydrogen, linear, branched or cyclic alkyl, aryl, substituted aryl, heteroaryl, haloalkyl like CF3, alkoxy, haloalkoxy, thioalkyl and halogen preferably chloro Formula I wherein R' and R" are same or different and is selected from linear.branched and cyclic alkyl (C1C4groups)preferably methyl R is selected from hydrogen, linear, branched or cyclic alkyl, aryl, substituted aryl, heteroaryl, haloalkyl like CF3, alkoxy, haloalkoxy, thioalkyl and halogen preferably chloro Formula II.
