151062-33-8

Basic information

• Product Name: 1-Pyrrolidineaceticacid,2-amino-5-oxo-,(S)-(9CI)
• Synonyms: 1-Pyrrolidineaceticacid,2-amino-5-oxo-,(S)-(9CI)
• CAS NO: 151062-33-8
• Molecular Formula: C6H10N2O3
• Molecular Weight: 158.16
• Product Categories: GLYCINESCAFFOLD
• Mol File: 151062-33-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Pyrrolidineaceticacid,2-amino-5-oxo-,(S)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidineaceticacid,2-amino-5-oxo-,(S)-(9CI)(151062-33-8)
• EPA Substance Registry System: 1-Pyrrolidineaceticacid,2-amino-5-oxo-,(S)-(9CI)(151062-33-8)

Safety Data

• Hazardous Substances Data: 151062-33-8(Hazardous Substances Data)

Upstream product

• 1042658-94-5 (S)-(2-amino-5-oxo-pyrrolidin-1-yl)-acetic acid tert-butyl ester 

Relevant articles and documents

Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain

Chemical modifications of dimiracetam, a bicyclic analogue of the nootropic drug piracetam, afforded a small set of novel derivatives that were investigated in in vivo models of neuropathic pain. Compounds 5, 7 and 8 displayed a very promising antihyperalgesic profile in rat models of neuropathic pain induced by both chronic constriction injury of the sciatic nerve and streptozotocin. The compounds completely reverted the reduction of pain threshold evaluated by the paw pressure test. Importantly these derivatives did not induce any behavioural impairment as evaluated by the rotarod test. These results suggest that compounds 5, 7 and 8 might represent novel and well-tolerated therapeutic agents for the relief of neuropathic pain.