151099-09-1

Basic information

• Product Name: 1,8-Naphthyridin-4-ol,6-ethoxy-7-methyl-(9CI)
• Synonyms: 1,8-Naphthyridin-4-ol,6-ethoxy-7-methyl-(9CI)
• CAS NO: 151099-09-1
• Molecular Formula: C11H12N2O2
• Molecular Weight: 204.22518
• Product Categories: ETHOXY
• Mol File: 151099-09-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,8-Naphthyridin-4-ol,6-ethoxy-7-methyl-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,8-Naphthyridin-4-ol,6-ethoxy-7-methyl-(9CI)(151099-09-1)
• EPA Substance Registry System: 1,8-Naphthyridin-4-ol,6-ethoxy-7-methyl-(9CI)(151099-09-1)

Safety Data

• Hazardous Substances Data: 151099-09-1(Hazardous Substances Data)

Usage

Class

Naphthyridine derivatives

Core structure

Naphthyridine

Substitution pattern

Ethoxy group at the 6-position and a methyl group at the 7-position

Type of molecule

Heterocyclic

Potential applications

Pharmacological and biological activities

Relevance

Medicinal chemistry and drug discovery

Status

Potential candidate for developing new therapeutic agents

Research needs

Further research to explore properties and potential uses

Upstream product

• 73101-81-2 ethyl 6-ethoxy-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate 

Relevant articles and documents

Condensed 4-aminopyridines with antirheumatic activity

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which one of A or B represents N and the other represents N or C--R3 ; R1 represents hydrogen, halo, alkyl, hydroxy, carboxyalkenyl, alkoxycarbonylalkenyl, hydroxyalkyl, carboxyalkyl, alkoxycarbonylalkyl, alkoxy, halogenated alkyl, carboxy, alkoxycarbonyl, alkanoylamino or carbamoylalkenyl; R2 represents hydrogen, alkyl, halo, alkoxy, hydroxy, alkanoyloxy, or phenoxy; R3 represents hydrogen or alkyl; R4 represents hydrogen, halo, alkoxycarbonyl, cyano, benzyloxycarbonyl, alkanoyl, benzoyl, alkyl, carboxy, alkylthio or carbamoyl; R5 represents hydrogen or alkyl; R9 represents hydrogen or alkyl; R10 represents phenyl, pyridyl or pyrimidinyl substituted by OR6 and optionally further substituted wherein R6 represents hydrogen, alkyl, alkoxycarbonyl or carbamoyl, alicyclic hydrocarbon, phenyl, cycloalkylalkyl, arylalkyl or pyridyl; or when R10 represents phenyl, OR6 represents a monosaccharide group or a disaccharide group; which are antirheumatic agents. Compositions containing these compounds and processes to prepare them are also disclosed.