151103-56-9Relevant articles and documents
SYNTHESIS OF 3-N-BUTYLPYRIDINE - A TOXIC METABOLITE OF THE FUNGUS Fusarium oxysporum AND ITS HOMOLOGUES
Goshaev, M. G.
, p. 391 - 393 (1993)
The interaction of the tri-n-butylphosphine complex of lithium di(3-pyridyl) copper(I) with 1-iodobutane and with other alkyl halides in ether at room temperature has given 3-n-butylpyridine and its homologues with yields of 82-89 percent.
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Burnell,R.H.,Medina,J.D.
, p. 307 - 316 (1971)
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Ligand interaction of sustituted pyridines with cytochrome P-450.
Born,Early
, p. 850 - 851 (1980)
A series of pyridyl ketones and alkyl pyridines was evaluated as type II ligands for cytochrome P-450. Activity as type II ligands was evaluated in terms of the lipid solubility and the pKa values of the compounds.
The structure of the calabash curare alkaloid calebassinine-1
Guggisberg,Prewo,Bieri,Hesse
, p. 2587 - 2597 (1982)
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An Annelated Mesoionic Carbene (MIC) Based Ru(II) Catalyst for Chemo- And Stereoselective Semihydrogenation of Internal and Terminal Alkynes
Bera, Jitendra K.,Choudhury, Joyanta,Das, Shubhajit,Dutta, Indranil,Pati, Swapan K.,Saha, Sayantani,Yadav, Suman
, p. 3212 - 3223 (2020/10/02)
The catalytic utility of [RuL1(CO)2I2] (1), containing an annelated π-conjugated imidazo-naphthyridine-based mesoionic carbene (MIC) ligand (L1), is evaluated for E-selective alkyne semihydrogenation. The precatalyst 1, in combination with 2 equiv of AgBArF, semihydrogenates a broad range of internal alkynes with molecular hydrogen (5 bar) in water. (E)-Alkenes are accessed in high yields, and a number of reducible functional groups are tolerated. A chelate MIC ligand and two cis carbonyls provide a well-defined platform at the Ru center for hydrogenation and isomerization. The loss of two iodides and the presence of two carbonyls render the Ru center electron deficient and thus the formation of metal vinylidenes with terminal alkynes is avoided. This is leveraged for the semihydrogenation of terminal alkynes by the same catalytic system in isopropyl alcohol. Reaction profile, isomerization, kinetic, and DFT studies reveal initial alkyne hydrogenation to a (Z)-alkene, which further isomerizes to an (E)-alkene via metal-catalyzed Z → E isomerization.
Methyl Hydrazinocarboxylate as a Practical Alternative to Hydrazine in the Wolff-Kishner Reaction
Cranwell, Philippa B.,Russell, Andrew T.,Smith, Christopher D.
, p. 131 - 135 (2015/12/26)
Herein we describe a facile protocol for the reduction of aromatic ketones and aldehydes to the corresponding methylene unit. The procedure involves isolation of a carbomethoxyhydrazone intermediate that is easily decomposed to the reduced product without the requirement for large quantities of pernicious hydrazine.
