151132-90-0

Basic information

• Product Name: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>-2,2-dideuterioacetate
• CAS NO: 151132-90-0
• Molecular Weight: 391.519
• Mol File: 151132-90-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>-2,2-dideuterioacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>-2,2-dideuterioacetate(151132-90-0)
• EPA Substance Registry System: (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl 2-<(tert-butoxycarbonyl)amino>-2,2-dideuterioacetate(151132-90-0)

Safety Data

• Hazardous Substances Data: 151132-90-0(Hazardous Substances Data)

Upstream product

• 65253-04-5 (-)-8-phenylmenthol 
• 42492-65-9 N-(tert-butoxycarbonyl)glycine-2,2-d₂ 

Downstream Products

• 134150-57-5 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (R)-2-<(tert-butoxycarbonyl)amino>-2-deuterioacetate 
• 117681-86-4 (1R,2S,5R)-2-(1-methyl-1-phenylethyl)-5-methylcyclohexyl (tert-butoxycarbonyl)aminoacetate 

Relevant articles and documents

Asymmetric induction in acyclic radical reactions: Enantioselective syntheses of (S)-2-deuterioglycine and (R)-2-deuterioglycine

The (-)-8-phenylmenthol esters of N-Boc-glycine and N-Boc-2,2-dideuterioglycine were brominated with N-bromosuccinimide and the bromo compounds were reduced with tri-n-butyldeuteriostannane and tri-n-butylstannane respectively, to give the chiral glycine derivatives in 90% optical yield. Hydrolysis yielded the amino acid without racemisation.