151151-30-3

Basic information

• Product Name: BETA-AMYLOID (32-35)
• Synonyms: AMYLOID BETA-PROTEIN FRAGMENT 32-35;H-ILE-GLY-LEU-MET-OH;ILE-GLY-LEU-MET;IGLM;BETA-AMYLOID (32-35);amyloid B-protein fragment 32-35*acetate;amyloid β-protein fragment 32-35;-Amyloid (32-35)
• CAS NO: 151151-30-3
• Molecular Formula: C21H40N4O7S
• Molecular Weight: 492.63
• Product Categories: Amyloid beta Protein Fragments;Neurodegenerative Disease Peptides;Neuropeptides;peptide
• Mol File: 151151-30-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 756.5±60.0 °C(Predicted)
• Appearance: /
• Density: 1.156±0.06 g/cm3(Predicted)
• Storage Temp.: −20°C
• PKA: 3.24±0.10(Predicted)
• CAS DataBase Reference: BETA-AMYLOID (32-35)(CAS DataBase Reference)
• NIST Chemistry Reference: BETA-AMYLOID (32-35)(151151-30-3)
• EPA Substance Registry System: BETA-AMYLOID (32-35)(151151-30-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 151151-30-3(Hazardous Substances Data)

Usage

General Description

BETA-AMYLOID (32-35) is a small fragment of the beta-amyloid peptide, which is a key component of amyloid plaques found in the brains of individuals with Alzheimer's disease. This specific fragment has been implicated in the neurotoxic effects of beta-amyloid and is thought to be involved in the disruption of neuronal function and the development of Alzheimer's disease. Research has shown that BETA-AMYLOID (32-35) can self-aggregate to form toxic oligomers and fibrils, leading to neuronal cell death and cognitive decline. Studying the properties and mechanisms of action of this specific fragment may provide insights into the pathogenesis of Alzheimer's disease and potential therapeutic interventions.