15121-83-2

Basic information

• Product Name: 2,2-BIS(HYDROXYMETHYL)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE
• Synonyms: 2,2-BIS(HYDROXYMETHYL)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE;2,2-bis(hydroxymethyl)-1,2,3,4-tetrahydronaphthalen-1-one
• CAS NO: 15121-83-2
• Molecular Formula: C12H14O3
• Molecular Weight: 206.24
• Mol File: 15121-83-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2-BIS(HYDROXYMETHYL)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-BIS(HYDROXYMETHYL)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(15121-83-2)
• EPA Substance Registry System: 2,2-BIS(HYDROXYMETHYL)-3,4-DIHYDRO-1(2H)-NAPHTHALENONE(15121-83-2)

Safety Data

• Hazardous Substances Data: 15121-83-2(Hazardous Substances Data)

Usage

Common Uses

Production of pharmaceuticals, polymers, and other industrial applications

Known For

High reactivity, ability to form strong bonds with other molecules, and use as a cross-linking agent in resins and adhesives

Contributions

Strength and durability in products, potential applications in organic synthesis and material science

Importance

Versatile and valuable chemical in the industry

Upstream product

• 50-00-0 formaldehyd 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 28539-02-8 1-Hydroxymethyl-1H-benzotriazole 

Relevant articles and documents

A mild and efficient bisaldolization of ketones and its application towards spirocyclic 1,3-dioxanes and novel 1,3,5-trioxocanes

Bisaldolization of aryl alkyl ketones as well as cyclic ketones with paraformaldehyde in the presence of a catalytic amount of L-proline and low concentration of aqueous sodium hydroxide has been developed in excellent yields. Further, these bisaldols are

Anionic, in situ generation of formaldehyde: A very useful and versatile tool in synthesis

(Chemical Equation Presented) A very simple, safe and powerful method for the in situ generation of formaldehyde at low temperature in anhydrous conditions is described. This new tool avoids the use of gaseous formaldehyde and is suitable for basic carbon nucleophiles which cannot be generated in aqueous reaction media. Various substrates, including organolithium reagents and enolates, underwent smooth hydroxymethylation showing the versatility of this process. A Wittig reaction was also carried out in high yield.