151221-95-3Relevant articles and documents
Synthesis and Evaluation of a Series of Benzylaniline Hydrochlorides as Potential Cytotoxic and Antimitotic Agents Acting by Inhibition of Tubulin Polymerization
Cushman, Mark,He, Hu-Ming,Lin, Chii M.,Hamel, Ernest
, p. 2817 - 2821 (2007/10/02)
Although certain substituted cis-stilbenes have displayed potent tubulin polymerization inhibitory activity and significant cytotoxicities in cancer cell cultures, these compounds have limited aqueous solubility and are therefore difficult to formulate fo