151222-07-0Relevant academic research and scientific papers
Application of a catalyst-free Domino Mannich/Friedel-Crafts alkylation reaction for the synthesis of novel tetrahydroquinolines of potential antitumor activity
Castillo, Juan-Carlos,Jiménez, Elizabeth,Portilla, Jaime,Insuasty, Braulio,Quiroga, Jairo,Moreno-Fuquen, Rodolfo,Kennedy, Alan R.,Abonia, Rodrigo
, p. 932 - 947 (2018/02/09)
A useful and efficient method to construct diversely substituted 1,2,3,4-tetrahydroquinolines in good to excellent yields has been developed through a catalyst-free Domino Mannich and intramolecular Friedel-Crafts alkylation reactions of N-arylamines with
Stilbene derivatives as anticancer agents
-
, (2008/06/13)
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can be utilized in a method of treating such cancers. Pharmaceu
Synthesis and Evaluation of a Series of Benzylaniline Hydrochlorides as Potential Cytotoxic and Antimitotic Agents Acting by Inhibition of Tubulin Polymerization
Cushman, Mark,He, Hu-Ming,Lin, Chii M.,Hamel, Ernest
, p. 2817 - 2821 (2007/10/02)
Although certain substituted cis-stilbenes have displayed potent tubulin polymerization inhibitory activity and significant cytotoxicities in cancer cell cultures, these compounds have limited aqueous solubility and are therefore difficult to formulate fo
