151222-67-2

Basic information

• Product Name: 1,4-difluoro-2,3-dinitrobenzene
• Synonyms: 1,4-difluoro-2,3-dinitrobenzene
• CAS NO: 151222-67-2
• Molecular Weight: 204.09
• Mol File: 151222-67-2.mol

Chemical Properties

• CAS DataBase Reference: 1,4-difluoro-2,3-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-difluoro-2,3-dinitrobenzene(151222-67-2)
• EPA Substance Registry System: 1,4-difluoro-2,3-dinitrobenzene(151222-67-2)

Safety Data

• Hazardous Substances Data: 151222-67-2(Hazardous Substances Data)

Upstream product

• 540-36-3 para-difluorobenzene 

Relevant articles and documents

A high-output, continuous selective and heterogeneous nitration of p -difluorobenzene

A practical continuous nitration process for 2,5-difluoronitrobenzene via nitration of p-difluorobenzene with fuming nitric acid in 98% yield has been developed. The excellent yield of this liquid/liquid biphasic reaction resulted from the advantages of a continuous flow system. The 2.0 equiv sulfuric acid could be used three times directly with product yields in the range of 96-98%, and further recycling of waste acid could be partly achieved by adjusting the concentration of sulfuric acid. Reaction time could be brought down to 2 min by increasing the reaction temperature and thereby taking advantage of superior mass and heat transfer of this continuous flow system.

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are heteroaryl compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. In one embodiment, the compounds provided herein are useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, including, but not limited to, e.g., neurological disorders, psychosis, schizophrenia, obesity, and diabetes