151273-51-7 Usage
Synthesis
A mixture of 5-aminoindole (120.0 g, 0.908 mol), acetonylacetone (200.0 mL, 1.70 mol), and toluene (400 mL) was heated at reflflux under nitrogen using a DeanStark trap for 6 h. The reaction was cooled and then poured through a silica gel fifilter ?(~ 2 kg) followed fifirst by hexanes (4 L) and then by 6% ether in hexanes to afford 133.3 g of a pink solid. Recrystallization of this solid in ether/hexanes afforded 126.1 g (66%) of the 2,5-dimethylpyrrole as an off-white solid.?Reference: Macor, J. E.; Chenard, B. L.; Post, R. J. J. Org. Chem. 1994, 59, 7496?7498.
Check Digit Verification of cas no
The CAS Registry Mumber 151273-51-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,2,7 and 3 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 151273-51:
(8*1)+(7*5)+(6*1)+(5*2)+(4*7)+(3*3)+(2*5)+(1*1)=107
107 % 10 = 7
So 151273-51-7 is a valid CAS Registry Number.
151273-51-7Relevant articles and documents
Substituted indole compounds having NOS inhibitory activity
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Page/Page column 64; 65; 67, (2010/11/24)
The present invention features inhibitors of nitric oxide synthase (NOS), particularly those that selectively inhibit neuronal nitric oxide synthase (nNOS) in preference to other NOS isoforms. The NOS inhibitors of the invention, alone or in combination w
INDOLE DERIVATIVES
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, (2008/06/13)
Compounds of the formula STR1 wherein Z is STR2 R 1 is STR3 X is O, NH, or S; A, B, D, E, and F are each independently C, N, O, or S; wherein the remaining variables are defined in the specification, and the pharmaceutically acceptable salts thereof. Thes
