151276-01-6Relevant academic research and scientific papers
Synthesis of novel chiral bidentate hydroxyalkyl-N-heterocyclic carbene ligands and their application in palladium-catalyzed Mizoroki-Heck couplings and asymmetric addition of diethylzinc to benzaldehyde
Faraji, Laleh,Jadidi, Khosrow,Notash, Behrouz
supporting information, p. 346 - 350 (2014/01/06)
A small library of new chiral bidentate hydroxyalkyl-imidazolium salts 1 is conveniently synthesized on multi-gram scale from inexpensive and commercially available chiral pool amino acids. The corresponding carbenes, generated by deprotonation of imidazolium salts 1, in combination with palladium(II) chloride were tested in the Mizoroki-Heck coupling reaction. The most significant results in terms of yields and reactivities were achieved with low catalyst loading. The catalytic activities of these imidazolium salts were also investigated in the asymmetric addition of diethylzinc to benzaldehyde. The use of MgO nanoparticles as an additive in conjunction with these ligands played a crucial role in increasing the efficiency of these reactions.
Synthesis of novel chiral diamino alcohols and their application in copper-catalyzed asymmetric allylic oxidation of cycloolefins
Faraji, Laleh,Samadi, Saadi,Jadidi, Khosrow,Notash, Behrouz
, p. 1989 - 1995 (2014/09/17)
The small library of new enantiomerically pure (S,S)-diamino alcohols 1 and their hydroxyldiamide precursors 2 were conveniently synthesized on a gram scale from inexpensive and commercially chiral pool amino acids. The catalytic and induced asymmetric ef
Fungal metabolites. XIII. Isolation and structural elucidation of new peptaibols, trichodecenins-I and -II from Trichoderma viride
Fujita,Wada,Iida,Nishimura,Kanai,Toyama
, p. 489 - 494 (2007/10/02)
Three new groups of peptaibols, trichodecenins, trichorovins and trichocellins, have been isolated from conidia of the fungus, Trichoderma viride. The structures of trichodecenins-I and -II were established by positive-ion fast-atom bombardment, collision-induced dissociation mass spectrometry and two-dimensional NMR spectroscopy. Trichodecenins-I and -II have a (Z)-4-decenoyl group, six amino acid residues and a leucinol moiety in the molecules. Trichodecenin-II was synthesized by the solution-phase method.
