151283-07-7

Upstream product

• 80-59-1 Tiglic acid 
• 1393661-58-9 (5S,6S)-5-hydroxy-6-((E)-2-((4S,5S)-2,2,5-trimethyl-1,3-dioxolan-4-yl)vinyl)-5,6-dihydro-2H-pyran-2-one 
• 1393661-59-0 C₁₀H₁₄O₅ 
• 1393661-52-3 (4S,E)-1-((4S,5S)-5-(benzyloxy)-2-phenyl-1,3-dioxan-4-yl)-4-((tert-butyldimethylsilyl)oxy)pent-1-en-3-one 
• 1393661-53-4 (3S,4S,E)-1-((4S,5S)-5-(benzyloxy)-2-phenyl-1,3-dioxan-4-yl)-4-((tert-butyldimethylsilyl)oxy)pent-1-en-3-ol 
• 1393661-50-1 (2S,3S,6S,7S,E)-2-(benzyloxy)oct-4-ene-1,3,6,7-tetraol 
• 1393661-54-5 (5S,6S,9S,10S,E)-10-(benzyloxy)-6,9-bis(tert-butyldimethylsilyloxy)-2,2,3,3,5,13,13,14,14-nonamethyl-4,12-dioxa-3,13-disilapentadec-7-ene 
• 1393661-55-6 (2S,3S,6S,7S,E)-2-(benzyloxy)-3,6,7-tris(tert-butyldimethylsilyloxy)oct-4-en-1-ol 
• 1393661-56-7 (2Z,4S,5S,6E,8S,9S)-methyl 4-(benzyloxy)-5,8,9-tris((tert-butyldimethylsilyl)oxy)deca-2,6-dienoate 
• 1393661-57-8 (5S,6S)-5-(benzyloxy)-6-((3S,4S,E)-3,4-dihydroxypent-1-en-1-yl)-5,6-dihydro-2H-pyran-2-one 
• 132039-54-4 (2S,3S)-2,3-dihydroxy-4-pentene 
• 134690-20-3 (5S,6R)-4-Pyrrolidin-1-yl-5-(tetrahydro-pyran-2-yloxy)-6-[(E)-2-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-vinyl]-5,6-dihydro-pyran-2-one 
• 134659-99-7 (5R,6S,3'S,4'S,1'E)-5,6-dihydro-5-hydroxy-6-(3',4'-isopropylidenedioxy-1'-pentenyl)-2H-pyran-2-one 

Downstream Products

• 97533-96-5 C₃₁H₃₂O₁₀ 

Relevant academic research and scientific papers

A cross-metathesis approach to the synthesis of (+)-phomopsolide B

Abstract The synthesis of phomopsolide B has been achieved using an olefin cross-metathesis (CM) reaction as key step. Two metathesis partners, enediol and 5-hydroxy vinyl lactone were prepared from l-ascorbic acid. This is the first report of using 5-hyd

Total synthesis of (+)-phomopsolide B

An enantiospecific total synthesis of polyhydroxy δ-pyrone natural product phomopsolide B is accomplished. The main feature of the synthesis is the installation of the required E-olefin by Horner-Emmons-Wordsworth reaction and the formation of the lactone

Total Synthesis of Natural (+)-Phomopsolide B, an Antifeedant against Elm Bark Beetle

The total synthesis of natural (+)-phomopsolid B (2) is described.A 5,6-dihydro-2H-pyran-2-one framework was constructed by coupling chiral aldehyde 4 and 4-oxygenated enaminoester 5.The resulting 5,6-dihydro-4-pyrrolidyl-2H-pyran-2-one (3) was converted to natural (+)-phomopsolide B (2) in several steps.