151294-96-1Relevant articles and documents
Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: Mediators of age-related macular degeneration
Lu, Liang,Gu, Xiaorong,Hong, Li,Laird, James,Jaffe, Keeve,Choi, Jaewoo,Crabb, John,Salomon, Robert G.
experimental part, p. 7548 - 7561 (2011/02/23)
Protein modifications in which the σ-amino group of lysyl residues is incorporated into a 2-(oωcarboxyethyl)pyrrole (CEP) are mediators of age-related macular degeneration (AMD). They promote both angiogenesis into the retina ('wet AMD') and geographic re