151322-34-8Relevant articles and documents
Palladium-catalyzed intramolecular hydroalkylation of unactivated olefins with dialkyl ketones
Wang, Xiang,Pei, Tao,Han, Xiaoqing,Widenhoefer, Ross A.
, p. 2699 - 2701 (2007/10/03)
(Matrix presented) Treatment of 3-butenyl heptyl ketone with substoichiometric amounts of PdCl2(CH3CN)2 (10 mol%), HCl (0.1 equiv), and CuCl2 (0.3 equiv) in dioxane at 70°C for 12 h in a sealed tube formed 2-hexylcyclohexanone in 77% isolated yield. A number of alkyl 3-butenyl ketones underwent hydroalkylation under these conditions to form 2-substituted cyclohexanones in moderate to good yield.