15135-21-4 Usage
Compound structure
1-pentofuranosylquinazoline-2,4(1H,3H)-dione is a chemical compound that combines a pentofuranosyl (a sugar) group with a quinazoline-2,4(1H,3H)-dione core.
Pharmacological applications
The compound has potential pharmacological applications due to its ability to interact with biological systems.
Biological activities
Quinazoline-2,4(1H,3H)-dione derivatives have diverse biological activities, including anticancer, antidiabetic, anti-inflammatory, and antiviral properties.
Pharmacokinetic properties
The addition of a sugar group, such as pentofuranosyl, can modulate the compound's pharmacokinetic properties and increase its bioavailability.
Therapeutic targets
Understanding the chemical and pharmacological properties of 1-pentofuranosylquinazoline-2,4(1H,3H)-dione can lead to the development of novel pharmaceutical agents for various therapeutic targets.
Check Digit Verification of cas no
The CAS Registry Mumber 15135-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,3 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15135-21:
(7*1)+(6*5)+(5*1)+(4*3)+(3*5)+(2*2)+(1*1)=74
74 % 10 = 4
So 15135-21-4 is a valid CAS Registry Number.
15135-21-4Relevant articles and documents
S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS
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Paragraph 0081; 0572, (2021/06/22)
Various embodiments provide STOPS? polymers that are S-antigen transport inhibiting oligonucleotide polymers, processes for making them and methods of using them to treat diseases and conditions. In some embodiments the STOPS? modified oligonucleotides include an at least partially phosphorothioated sequence of alternating A and C units having modifications as described herein. The sequence independent antiviral activity against hepatitis B of embodiments of STOPS? modified oligonucleotides, as determined by HBsAg Secretion Assay, is an EC50 that is less than 100 nM.
The synthesis of some quinazoline nucleosides.
Stout,Robins
, p. 1219 - 1225 (2007/10/05)
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