151378-30-2

Basic information

• Product Name: 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI)
• Synonyms: 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI)
• CAS NO: 151378-30-2
• Molecular Formula: C7H9F3N2O2
• Molecular Weight: 210.1537696
• Product Categories: ACETYLHALIDE
• Mol File: 151378-30-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 423.6±45.0 °C(Predicted)
• Appearance: /
• Density: 1.440±0.06 g/cm3(Predicted)
• PKA: 15.17±0.20(Predicted)
• CAS DataBase Reference: 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI)(151378-30-2)
• EPA Substance Registry System: 2-Pyrrolidinecarboxamide, 1-(trifluoroacetyl)-, (2S)- (9CI)(151378-30-2)

Safety Data

• Hazardous Substances Data: 151378-30-2(Hazardous Substances Data)

Upstream product

• 117368-39-5 Tfa-DL-Pro-NH2 
• 2812-47-7 pyrrolidine-2-carboxylic acid amide 
• 407-25-0 trifluoroacetic anhydride 
• 7531-52-4 L-prolinamide 
• 5626-64-2 DL-Pro-NCA 

Relevant articles and documents

Vildagliptin impurity compound and preparation method thereof, detection method and application

The invention relates to a Vildagliptin impurity compound and a preparation method thereof, a detection method and application. The Vildagliptin impurity compound has a structure as shown in the formula (I), wherein R1 is polyhalogenated C1-C4 lower alkyl or CH2R3, and R3 is five-membered/six-membered heterocyclic radical containing an N atom. The heterocyclic radical can be optionally replaced with CN or CONH2. The compound, as a reference substance or standard substance of related substances, can be used in quality control of a Vildagliptin preparation.