151387-05-2 Usage
Uses
Used in Pharmaceutical Industry:
(α1S,α4S,2S,5S)-2,5-DiMethyl-3,6-dioxo-α1,α4-bis(2-phenylethyl)-1,4-piperazinediacetic Acid 1,4-Diethyl Ester is used as an impurity in the production of Ramipril (R111000), an antihypertensive agent. It is important for the pharmaceutical industry to monitor and control the presence of this impurity to ensure the safety and efficacy of the final drug product. The compound's presence in Ramipril is due to its inhibitory activities towards the angiotensin-converting enzyme (ACE), which plays a crucial role in the regulation of blood pressure.
Check Digit Verification of cas no
The CAS Registry Mumber 151387-05-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,1,3,8 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 151387-05:
(8*1)+(7*5)+(6*1)+(5*3)+(4*8)+(3*7)+(2*0)+(1*5)=122
122 % 10 = 2
So 151387-05-2 is a valid CAS Registry Number.
151387-05-2Relevant academic research and scientific papers
Formation of N,N'-bis -3,6-S-dimethyl-2,5-diketopiperazine during the reaction of ethyl α(S)-benzenebutanoate with di-t-butyl dicarbonate
Dikshit, Dinesh K,Panday, Sharad K
, p. 788 - 789 (2007/10/02)
Reaction of ethyl (α(S)-benzenebutanoate with di-t-butyl dicarbonate in the presence of triethylamine and DMAP gives N,N'-bis-3,6-S-di-methyl-2,5-diketopiperazine in a quantitative yield.
