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1-(2-chloroethyl)-3-(2-methoxyphenyl)-1-nitrosourea, commonly known as nimustine, is a chemotherapy drug that belongs to the class of alkylating agents. It is characterized by its ability to inhibit the growth of cancer cells and is particularly effective in treating brain tumors due to its capacity to cross the blood-brain barrier. Nimustine is administered intravenously and is recognized for its relatively low toxicity compared to other chemotherapy drugs, although it may still cause side effects such as nausea, vomiting, and myelosuppression.

15145-41-2

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15145-41-2 Usage

Uses

Used in Anticancer Applications:
Nimustine is used as an anticancer agent for the treatment of various types of cancer, including brain tumors, lung cancer, and lymphoma. It works by inhibiting the growth of cancer cells, making it a valuable addition to the arsenal of chemotherapy drugs for combating these diseases.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, nimustine is used as a key component in the development of cancer treatment regimens. Its ability to cross the blood-brain barrier and its relatively low toxicity make it a preferred choice for patients with brain tumors and other malignancies.
Used in Research and Development:
Nimustine is also utilized in research and development for the study of cancer biology and the development of new cancer treatments. Its unique properties and effectiveness against various types of cancer make it an important compound for further investigation and potential improvements in cancer therapy.

Check Digit Verification of cas no

The CAS Registry Mumber 15145-41-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,1,4 and 5 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15145-41:
(7*1)+(6*5)+(5*1)+(4*4)+(3*5)+(2*4)+(1*1)=82
82 % 10 = 2
So 15145-41-2 is a valid CAS Registry Number.

15145-41-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Urea,N-(2-chloroethyl)-N'-(2-methoxyphenyl)-N-nitroso-

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:15145-41-2 SDS

15145-41-2Downstream Products

15145-41-2Relevant academic research and scientific papers

The relationship between solvatochromic properties and in silico ADME parameters of new chloroethylnitrosourea derivatives with potential anticancer activity and their β-Cyclodextrin complexes

Fisli, Hassina,Hennig, Andreas,Chelaghmia, Mohamed Lyamine,Abdaoui, Mohamed

supporting information, (2021/02/27)

In view of the anticancer effect of nitrosoureas a set of four new N-(2-chloroethyl)-N-nitrosourea (CENU) derivatives was synthesized. An in silico absorption, distribution, metabolism, excretion and toxicity (ADME/Tox) prediction study revealed that the

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