1514833-77-2Relevant academic research and scientific papers
Cu(I)-NHC catalyzed Asymmetric Silyl transfer to unsaturated Lactams and Amides
Pace, Vittorio,Rae, James P.,Procter, David J.
supporting information, p. 476 - 479 (2014/04/03)
The first asymmetric silylation of unsaturated lactams and amides using Cu(I)-NHC catalysts and PhMe2SiBpin has been accomplished. The method has been exploited in an expedient asymmetric synthesis of the (R)-enantiomer of the nootropic drug oxiracetam.
