151487-08-0

Basic information

• Product Name: Ampelopsin F
• Synonyms: Ampelopsin F;(5R,10S,11S,12R)-10,11-Dihydro-11,12-bis(4-hydroxyphenyl)-5,10-methano-5H-dibenzo[a,d]cycloheptene-1,3,6,8-tetrol
• CAS NO: 151487-08-0
• Molecular Formula: C28H22O6
• Molecular Weight: 454.47
• Mol File: 151487-08-0.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ampelopsin F(CAS DataBase Reference)
• NIST Chemistry Reference: Ampelopsin F(151487-08-0)
• EPA Substance Registry System: Ampelopsin F(151487-08-0)

Safety Data

• Hazardous Substances Data: 151487-08-0(Hazardous Substances Data)

Usage

General Description

Ampelopsin F, also known as dihydromyricetin, is a natural flavonoid compound found in Ampelopsis grossedentata. It is known for its antioxidant, anti-inflammatory, and hepatoprotective properties. Studies have shown that Ampelopsin F has potential as a treatment for alcohol-related liver damage, as it has been found to reduce the effects of alcohol on the liver and decrease alcohol consumption in animal models. Additionally, it has been investigated for its potential anti-cancer effects, with some studies suggesting that it may inhibit the growth of certain types of cancer cells. Overall, Ampelopsin F shows promise as a therapeutic compound with a range of potential health benefits.

Upstream product

• 253435-07-3 5-{6-hydroxy-2-(4-hydroxyphenyl)-4-[2-(4-hydroxyphenyl)vinyl]-2,3-dihydrobenzofuran-3-yl}benzene-1,3-diol 
• 1334714-28-1 C₃₂H₃₀O₆ 

Relevant articles and documents

Biosynthesis of resveratrol dimers by regioselective oxidative coupling reaction

A wide array of natural resveratrol dimers was prepared by the regioselective oxidative coupling reaction of 3,5-di-(tert-butyl)resveratrol using several types of metal oxidants (Ag2O, Ag2CO 3, MnO2, and FeCl36H2O) in different solvent systems (benzene-acetone and dichloromethane). Subsequent debutylation of these coupling products resulted in racemic pallidol and ampelosin F. Georg Thieme Verlag Stuttgart.

SYNTHESIS OF RESVERATROL-BASED NATURAL PRODUCTS

Processes for synthesizing reveratrol-based oligomers are provided. In addition, reservatrol-based oligomer compounds free of plant extract are provided.

Total synthesis of resveratrol-based natural products: A chemoselective solution

Despite the attention paid to resveratrol (1) owing to its potent biological activity, little effort has been devoted to studying resveratrol-based oligomers (such as 2-4). The first general synthetic approach is outlined for accessing the carbogenic diversity possessed by this family of compounds. (Chemical Equation Presented).