Cas 1514927-01-5,1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone

1514927-01-5

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Basic information

Product Name: 1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone
Synonyms: 1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone
CAS NO:1514927-01-5
Molecular Formula:
Molecular Weight: 292.312
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone(CAS DataBase Reference)
NIST Chemistry Reference: 1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone(1514927-01-5)
EPA Substance Registry System: 1-(8-quinolinyl)-4-(3-fluorophenyl)azetidinone(1514927-01-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1514927-01-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1514927-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,1,4,9,2 and 7 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1514927-01:
(9*1)+(8*5)+(7*1)+(6*4)+(5*9)+(4*2)+(3*7)+(2*0)+(1*1)=155
155 % 10 = 5
So 1514927-01-5 is a valid CAS Registry Number.

1514927-01-5Upstream product

1329286-21-6 3-(3-fluorophenyl)-N-(8-quinolinyl)propanamide

1514927-01-5Downstream Products

1514927-01-5Relevant academic research and scientific papers

Palladium-catalyzed unactivated c(sp3)-h bond activation and intramolecular amination of carboxamides: A new approach to β-lactams

Sun, Wen-Wu,Cao, Pei,Mei, Ren-Qiang,Li, Yue,Ma, Yuan-Liang,Wu, Bin

, p. 480 - 483 (2014)

An efficient method to synthesize the β-lactams with high regioselectivity via Pd-catalyzed C(sp3)-H bond activation and intramolecular amination of simple and readily available aminoquinoline carboxamides was demonstrated. C6F5I plays a signif

Stereoselective synthesis of diazabicyclic β-lactams through intramolecular amination of unactivated C(sp3)-H bonds of carboxamides by palladium catalysis

Zhang, Shi-Jin,Sun, Wen-Wu,Cao, Pei,Dong, Xiao-Ping,Liu, Ji-Kai,Wu, Bin

, p. 956 - 968 (2016/02/19)

An efficient C(sp3)-H bond activation and intramolecular amination reaction via palladium catalysis at the β-position of carboxyamides to make β-lactams was described. The investigation of the substrate scope showed that the current reaction conditions favored activation of the β-methylene group. Short sequences were developed for preparation of various diazabicyclic β-lactam compounds with this method as the key step from chiral proline and piperidine derivatives.

N-quinolyl-substituted β-lactam compound and its pharmaceutical compositions and synthetic method and application

-

Paragraph 0104-0107, (2016/10/09)

The invention discloses an N-quinolyl substituted beta-lactam compound as shown in a general formula (I), wherein R and R refer to mutually independent H or C1-12 straight-chain or branched-chain hydrocarbonyl, aryl, alkoxy, acyloxy or amino; R r

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