151539-46-7

Basic information

• Product Name: (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene ]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione
• Synonyms: (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene ]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione
• CAS NO: 151539-46-7
• Molecular Formula: C20H24N4O4
• Molecular Weight: 384.43
• Mol File: 151539-46-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 499°Cat760mmHg
• Flash Point: 255.6°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 4.74E-12mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene ]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene ]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione(151539-46-7)
• EPA Substance Registry System: (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene ]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione(151539-46-7)

Safety Data

• Hazardous Substances Data: 151539-46-7(Hazardous Substances Data)

Usage

Description

(8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione is a complex chemical compound belonging to the purine class. It features a cyclohexadiene ring and two propyl side chains, which contribute to its unique properties and potential applications.

Uses

Used in Pharmaceutical Industry:
(8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione is used as a potent inhibitor of xanthine oxidase for the treatment of conditions characterized by high uric acid levels, such as gout. Its ability to inhibit the enzyme responsible for uric acid production makes it a potential drug candidate for managing gout and related symptoms.
Used in Drug Development:
Due to its unique structure and properties, (8E)-8-[(2Z)-2-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)ethylidene]-7-methyl-1,3-dipropyl-9H-purine-2,6-dione is a promising target for further study and potential drug development. Researchers may explore its potential in treating other conditions related to purine metabolism or xanthine oxidase activity, as well as investigating its possible synergistic effects with other medications.

InChI:InChI=1/C20H24N4O4/c1-4-10-23-18-17(19(27)24(11-5-2)20(23)28)22(3)16(21-18)9-7-13-6-8-14(25)15(26)12-13/h6-9,12,21,26H,4-5,10-11H2,1-3H3/b13-7-,16-9+

Upstream product

• 141807-96-7 (E)-8-(3,4-dimethoxystyryl)-7-methyl-1,3-dipropylxanthine 

Relevant articles and documents

Xanthine derivatives

The present invention relates to novel xanthine derivatives and pharmaceutically acceptable salts thereof, represented by Formula (I): STR1 wherein R1, R2, and R3 independently represent hydrogen, lower alkyl, lower alkeny