1515491-24-3

Basic information

• Product Name: 1-(benzo[d]oxazol-4-yl)ethan-1-one
• Synonyms: 1-(benzo[d]oxazol-4-yl)ethan-1-one
• CAS NO: 1515491-24-3
• Molecular Weight: 161.16
• Mol File: 1515491-24-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(benzo[d]oxazol-4-yl)ethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzo[d]oxazol-4-yl)ethan-1-one(1515491-24-3)
• EPA Substance Registry System: 1-(benzo[d]oxazol-4-yl)ethan-1-one(1515491-24-3)

Safety Data

• Hazardous Substances Data: 1515491-24-3(Hazardous Substances Data)

Upstream product

• 4502-10-7 2'-amino-3'-hydroxyacetophenone 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 1620075-80-0 C₂₀H₁₆BrN₃O₄ 

Relevant articles and documents

One-pot oxidative hydrolysis-oxidative cleavage of 7-borylindoles enables access to: O -amidophenols and 4-acylbenzoxazoles

7-Borylindoles undergo a one-pot oxidative-hydrolysis of the arylboronate and oxidative cleavage of the indole C2-C3 double bond to afford o-amidophenol derivatives. Subsequent cyclisation delivers benzoxazoles bearing an acyl group at C4, a substitution pattern common to fungal-derived benzoxazole alkaloids. Using 7-borylindoles as substrates to access functionalised o-amidophenols circumvents the difficult preparation of these compounds from arenes, streamlining access to substituted 4-acylbenzoxazoles in the process.