151558-63-3Relevant academic research and scientific papers
SYNTHESIS OF POTENTIAL ANTINEOPLASTICS BY CONDENSATION OF PHTHALIC ANHYDRIDE WITH 4-BIS(2-CHLOROETHYL)AMINOPHENYLACETIC ACID
Pisarenko, L. M.,Nikulin, V. I.,Sveshnikov, N. N.
, p. 2061 - 2067 (1992)
Indandione, its enol acetate, and the products of a parallel reaction - a mixture of isomeric acids E, Z-5, and phthalide - are formed in the reaction of substituted phenylacetic acid with phthalic anhydride in acetic anhydride and triethylamine. 2-Substituted indandione derivatives were obtained. Keywords: arylindan-1,3-dione, anhydride condensation, synthesis, 3-arylidenephthalide, mass spectrum, PMR, 13C NMR, antineoplastic activity.
