1515829-91-0

Basic information

• Product Name: N′-[2-nitro-5-(trifluoromethyl)phenyl]-N′-phenylbenzohydrazide
• Synonyms: N′-[2-nitro-5-(trifluoromethyl)phenyl]-N′-phenylbenzohydrazide
• CAS NO: 1515829-91-0
• Molecular Weight: 401.345
• Mol File: 1515829-91-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N′-[2-nitro-5-(trifluoromethyl)phenyl]-N′-phenylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N′-[2-nitro-5-(trifluoromethyl)phenyl]-N′-phenylbenzohydrazide(1515829-91-0)
• EPA Substance Registry System: N′-[2-nitro-5-(trifluoromethyl)phenyl]-N′-phenylbenzohydrazide(1515829-91-0)

Safety Data

• Hazardous Substances Data: 1515829-91-0(Hazardous Substances Data)

Upstream product

• 532-96-7 N-benzoyl-N'-phenylhydrazine 
• 402-12-0 2-fluoro-1-nitro-4-(trifluoromethyl)benzene 

Downstream Products

• 1244508-21-1 1,3-diphenyl-7-(trifluoromethyl)-1,4-dihydrobenzo[e][1,2,4]triazin-4-yl 

Relevant articles and documents

Route to benzo- and pyrido-fused 1,2,4-triazinyl radicals via N ′-(Het)aryl- N ′-[2-nitro(het)aryl]hydrazides

A two-step route to 1,3-disubstituted benzo- and pyrido-fused 1,2,4-triazinyl radicals is presented. The route involves the N′-(2-nitroarylation) of easily prepared N′-(het)arylhydrazides via nucleophilic aromatic substitution of 1-halo-2-nitroarenes, which in most cases gives N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides in good yields. Mild reduction of the nitro group followed by an acid-mediated cyclodehydration gives the fused triazines, which upon alkali treatment afford the desired radicals. Fifteen examples of radicals are presented bearing a range of substituents at N-1, C-3, and C-7, including the pyrid-2-yl and 8-aza analogues. This route to the N′-(het)aryl-N′-[2-nitro(het)aryl]hydrazides, which works well with benzo- and picolinohydrazides, required a modification for aceto- and trifluoroacetohydrazides that involved a multistep synthesis of asymmetrically 1,1-diaryl-substituted hydrazines.